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Comment
. 2014 Oct;11(10):580-1.
doi: 10.1038/nrgastro.2014.161. Epub 2014 Sep 9.

Liver: Acute-on-chronic liver failure--no longer an entity without definition

R Todd Stravitz  1
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Liver: Acute-on-chronic liver failure--no longer an entity without definition

R Todd Stravitz. Nat Rev Gastroenterol Hepatol. 2014 Oct.

Abstract

Although clinicians instinctively recognise acute-on-chronic liver failure (ACLF), heretofore we have had no way of accurately studying the syndrome, as no definition of this entity existed. A consortium of European centres has finally offered a definition of ACLF and proposed a prognostic index based upon easily obtained features of patients with decompensated cirrhosis.

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