Mechanisms of seizure disorders
- PMID: 2520131
Mechanisms of seizure disorders
Abstract
Epilepsy, one of the most common neurologic disorders treated by veterinarians, is also one of the least understood. A dysregulation of neural excitability appears to underlie most seizures; yet, it is still not clear whether the disorder is one of excess excitation, failure of inhibition, or a combination of both. This paper presents normal neural physiology followed by current theories regarding the pathophysiology of epilepsy so that the reader may better understand the rationale explained in later chapters regarding the choice of anticonvulsant therapies.
Similar articles
-
The pathophysiology of epilepsy.Cornell Vet. 1981 Apr;71(2):221-47. Cornell Vet. 1981. PMID: 6260428 Review.
-
Seizures: classification, etiologies, and pathophysiology.Clin Tech Small Anim Pract. 1998 Aug;13(3):119-31. doi: 10.1016/S1096-2867(98)80033-9. Clin Tech Small Anim Pract. 1998. PMID: 9775502 Review.
-
[Seizure disorders in the dog. 1. Clinical features and differential diagnosis].Tierarztl Prax. 1995 Dec;23(6):596-602. Tierarztl Prax. 1995. PMID: 8585079 Review. German.
-
Canine epilepsy: what can we learn from human seizure disorders?Vet J. 2006 Sep;172(2):207-17. doi: 10.1016/j.tvjl.2005.07.001. Epub 2005 Sep 12. Vet J. 2006. PMID: 16154785 Review.
-
When to start drug treatment for childhood epilepsy: the clinical-epidemiological evidence.Eur J Paediatr Neurol. 2009 Mar;13(2):93-101. doi: 10.1016/j.ejpn.2008.02.010. Epub 2008 Jun 24. Eur J Paediatr Neurol. 2009. PMID: 18567515 Review.