Anticonvulsant drugs used in the treatment of epilepsy
- PMID: 2520134
Anticonvulsant drugs used in the treatment of epilepsy
Abstract
The pharmacology of anticonvulsant drugs is reviewed with emphasis placed on the treatment of canine and feline epilepsy. Due to pharmacokinetic reasons, only phenobarbital, primidone, and, with certain limitations, the benzodiazepines can be used in dogs. Bromides may be given additionally in cases that cannot be controlled with phenobarbital or promidone therapy. In cats, diazepam has been shown to be very useful because no tolerance develops to the antiepileptic effect in this species.
Similar articles
-
[Pharmacologic principles in the treatment of epilepsy in the dog and cat].Tierarztl Prax. 1985;13(4):541-9. Tierarztl Prax. 1985. PMID: 3834646 German.
-
Idiopathic epilepsy in dogs and cats.Vet Clin North Am Small Anim Pract. 2010 Jan;40(1):161-79. doi: 10.1016/j.cvsm.2009.09.004. Vet Clin North Am Small Anim Pract. 2010. PMID: 19942062 Review.
-
Clinical management of epilepsy of dogs and cats.Probl Vet Med. 1989 Oct-Dec;1(4):578-95. Probl Vet Med. 1989. PMID: 2520135 Review.
-
Veterinarians' preferences for anticonvulsant drugs for treating seizure disorders in dogs and cats.Aust Vet J. 2009 Nov;87(11):445-9. doi: 10.1111/j.1751-0813.2009.00509.x. Aust Vet J. 2009. PMID: 19857237
-
[Insufficient success in the treatment of epilepsy--mistakes in therapy or resistance to therapy?].Dtsch Tierarztl Wochenschr. 1992 Oct;99(10):407-10. Dtsch Tierarztl Wochenschr. 1992. PMID: 1425317 Review. German.
Cited by
-
Antiepileptic Drug Withdrawal in Dogs with Epilepsy.Front Vet Sci. 2015 Aug 10;2:23. doi: 10.3389/fvets.2015.00023. eCollection 2015. Front Vet Sci. 2015. PMID: 26664952 Free PMC article.
-
Is switching from brand name to generic formulations of phenobarbital associated with loss of antiepileptic efficacy?: a pharmacokinetic study with two oral formulations (Luminal(®) vet, Phenoleptil(®)) in dogs.BMC Vet Res. 2013 Oct 9;9:202. doi: 10.1186/1746-6148-9-202. BMC Vet Res. 2013. PMID: 24107313 Free PMC article. Clinical Trial.
-
The Anticonvulsant Effects of Ketogenic Diet on Epileptic Seizures and Potential Mechanisms.Curr Neuropharmacol. 2018;16(1):66-70. doi: 10.2174/1570159X15666170517153509. Curr Neuropharmacol. 2018. PMID: 28521671 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Medical
Miscellaneous