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. 2015 May;20(3):253-7.
doi: 10.1111/anec.12209. Epub 2014 Sep 9.

The effect of hemodialysis on electrocardiographic parameters

Ramazan Astan  1 , Ibrahim Akpinar  2 , Adnan Karan  3 , Fehmi Kacmaz  4 , Erdogan Sokmen  5 , Erkan Baysal  6 , Ozcan Ozeke  3 , Mehmet Timur Selçuk  3
Affiliations

The effect of hemodialysis on electrocardiographic parameters

Ramazan Astan et al. Ann Noninvasive Electrocardiol. 2015 May.

Abstract

Background: Cardiovascular complications are the leading causes of premature deaths in hemodialysis patients. Due to rapid changes in volume and electrolyte concentration following dialysis, the some electrocardiographic (ECG) changes or arrhythmias might be seen.

Objective: To investigate the acute effects of hemodialysis on the ECG parameters in patients with chronic end-stage renal disease (ESRD).

Method: We included the consecutive ESRD patients who underwent a hemodialysis. Before and after hemodialysis, some 12 lead ECG parameters were analyzed by two different cardiologists by using electronic digital caliper device.

Results: A total of 62 patients (mean 52 ± 15 years; 65% male) with ESRD undergoing hemodialysis were recruited to the study. P-wave amplitude, QRS amplitude, QRS duration, QTc dispersion, the sum of amplitudes in V1S + V5R derivations, total QRS amplitude, and duration were significantly greater in posthemodialysis patients compared to the prehemodialysis ones. However, T-wave amplitude and QTc duration were significantly lower in posthemodialysis patients.

Conclusion: The ECG changes including prolangated QRS and increased QTc interval after hemodialysis should be kept in mind and assessed carefully in ESRD patients. Prolongation of these parameters may prove to be a further noninvasive marker of susceptibility to ventricular arrhythmias.

Keywords: ECG; electrocardiography; hemodialysis.

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Comment in

  • P-wave changes in hemodialysis patients: reply to Marano et al.
    Astan R, Ozeke O. Astan R, et al. Ann Noninvasive Electrocardiol. 2015 May;20(3):301-2. doi: 10.1111/anec.12248. Epub 2014 Dec 24. Ann Noninvasive Electrocardiol. 2015. PMID: 25545195 Free PMC article. No abstract available.
  • Hemodialysis affects interatrial conduction.
    Marano M, D'Amato A, de Luna AB, Baranchuk A. Marano M, et al. Ann Noninvasive Electrocardiol. 2015 May;20(3):299-300. doi: 10.1111/anec.12252. Epub 2014 Dec 26. Ann Noninvasive Electrocardiol. 2015. PMID: 25545395 Free PMC article. No abstract available.

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