Seborrheic pemphigoid

Abstract

Seborrheic pemphigoid (SP), first described in 1969 by Schnyder, is a peculiar variant of BP which clinically resembles pemphigus erythematosus, since it is characterized by ruptured bullae and erosions covered with crusts involving the seborrheic areas. To the best of our knowledge, from the first description only four other cases of SP have been reported, of which two are in the English literature. We report an additional case of SP in a 56-year-old man with cervical spondylogenic myelopathy with very impaired mobility.

Figure 1

Several erosions (some of which with a peripheral epithelial collarette) and hematic and serous crusts on a slightly erythematous background on forehead (a), right periauricular region (b), and interscapular area (c); a flaccid blister (arrow) is visible under the right ear lobe (b).

Figure 2

Subepidermal bulla containing eosinophils with an eosinophilic inflammatory cell infiltrate in the superficial dermis (H and E staining, magnification ×100) (a); detail of eosinophils in the subepidermal blister (H and E staining, magnification ×400) (b). Direct immunofluorescence tests show deposition of IgG (c) and C3 (d) at the basement membrane zone (200x).