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Review
. 2014 Dec;16(12):1013-21.
doi: 10.1016/j.micinf.2014.09.001. Epub 2014 Sep 6.

Viral RNA recognition by the Drosophila small interfering RNA pathway

Zamira Guerra Soares  1 , André Nicolau Aquime Gonçalves  1 , Karla Pollyanna Vieira de Oliveira  1 , João Trindade Marques  2
Affiliations
Free article
Review

Viral RNA recognition by the Drosophila small interfering RNA pathway

Zamira Guerra Soares et al. Microbes Infect. 2014 Dec.
Free article

Abstract

Viral RNA is a common activator of antiviral responses. In this review, we dissect the mechanism of viral RNA recognition by the small interfering RNA pathway in Drosophila melanogaster. This antiviral response in fruit flies can help understand general principles of nucleic acid recognition.

Keywords: Drosophila melanogaster; RNA interference; Small interfering RNA; Viral infection; dsRNA.

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