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. 2012 Dec;29(4):440-3.
doi: 10.5152/balkanmedj.2012.076. Epub 2012 Dec 1.

Double primary tumors-renal cell carcinoma and duodenal mucinous adenocarcinoma

Nada Vuckovic  1 , Bojana Andrejic  2 , Matilda Djolai  1 , Srdjan Zivojinov  3 , Katarina Sarcev  4 , Dejan Vuckovic  5
Affiliations

Double primary tumors-renal cell carcinoma and duodenal mucinous adenocarcinoma

Nada Vuckovic et al. Balkan Med J. 2012 Dec.

Abstract

A 59-year old patient was admited to the Gastroenterology Clinic with the signs of gastrointestinal bleeding. Computerized tomography (CT) and a barium-meal radiography revealed a circumferential nodular wall narrowing and incomplete stricture at the D2 part of the duodenum. CT also showed a poorly demarcated mass in the upper and lower poles of the left kidney. During the operation, the whole kidney together with the tumor was removed and also a part of the duodenum. Morphological features of both tumors were typical and distinctive enough to set the diagnosis of two independent primary tumors. The possibility of one being the metastasis of the other was excluded. The diagnosis of double primary malignant neoplasms - renal cell carcinoma and duodenal mucinous adenocarcinoma was made.

Keywords: Duodenal cancer; mucinous adenocarcinoma; multiple primary neoplasms; renal cell carcinoma.

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Figures

Figure 1.
Figure 1.
Barium meal radiography of the duodenum
Figure 2.
Figure 2.
Computerized tomography of the abdomen. Arrow points to the tumor
Figure 3.
Figure 3.
Microscopic appearance of renal cell carcinoma and duodenal mucinous adenocarcinoma, a) clear cell area of RCC (HE staining, 50×), b) clear cell and eosinophilic component of RCC (HE staining, 50×), c) RCC tumor cells do not penetrate capsule (HE staining, 50×) d) duodenal mucinous adenocarcinoma (HE staining, 50×) HE: hematoxylin and eosin, RCC: Renal cell carcinoma
See this image and copyright information in PMC

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