Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Jun;47(3):298-301.
doi: 10.5090/kjtcs.2014.47.3.298. Epub 2014 Jun 5.

Resection of Intrapericardial Schwannoma Co-Existing with Thymic Follicular Hyperplasia through Sternotomy without Cardiopulmonary Bypass

Affiliations
Case Reports

Resection of Intrapericardial Schwannoma Co-Existing with Thymic Follicular Hyperplasia through Sternotomy without Cardiopulmonary Bypass

Jae Ho Chung et al. Korean J Thorac Cardiovasc Surg. 2014 Jun.

Abstract

A 35-year-old man was admitted to Korea University Anam Hospital for evaluation of intermittent chest pain. Computed tomography of the chest showed enlargement of a previously identified anterior mediastinal mass and also a well-defined, circumscribed mass in the subcarinal area, surrounded by the roof of the left atrium, right pulmonary artery, and the carina. Complete resection of the intrapericardial tumor was performed through median sternotomy without cardiopulmonary bypass. Pathologic examination identified the tumor as schwannoma, of an ancient type, diffusely positive for the S-100 antigen. Unlike other reported cases, grossly, the tumor did not seem to be involved with any nerve.

Keywords: 1. Schwannoma; 2. Mediastinal neoplsms; 3. Pericardium; 4. Sternotomy; 5. Benign neoplasm.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
(A) Constrast enhanced chest computed tomography (CT) and (B) three dimensional CT reconstruction showing the well-demarcated margin of the mass and its location between the posterior wall of the left atrium, right pulmonary artery, and the carina. (C) A diffusely enlarged anterior mediastinal mass was also seen in chest CT.
Fig. 2
Fig. 2
Intraoperative findings. (A) About 2.5×2.5×2 cm in size round tumor was located just posterior to the roof of the left atrium, and between the aorta and the main pulmonary artery. (B) Macroscopic view of the tumor.
Fig. 3
Fig. 3
Histopathologic findings. (A) The spindle cells show palisading arrangement (H&E, ×100). (B) The tumor cells are diffusely and strongly positive for S100 immunohistochemical stain in nucleus and cytoplasm (H&E, ×200).

References

    1. Pilavaki M, Chourmouzi D, Kiziridou A, Skordalaki A, Zarampoukas T, Drevelengas A. Imaging of peripheral nerve sheath tumors with pathologic correlation: pictorial review. Eur J Radiol. 2004;52:229–39. - PubMed
    1. Skovronsky DM, Oberholtzer JC. Pathologic classification of peripheral nerve tumors. Neurosurg Clin N Am. 2004;15:157–66. - PubMed
    1. Marchevsky AM. Mediastinal tumors of peripheral nervous system origin. Semin Diagn Pathol. 1999;16:65–78. - PubMed
    1. Hashimoto T, Eguchi S, Nakayama T, Ohzeki H, Hayashi J. Successful removal of massive cardiac neurilemoma with cardiopulmonary bypass. Ann Thorac Surg. 1998;66:553–5. - PubMed
    1. Forbes AD, Schmidt RA, Wood DE, Cochran RP, Munkenbeck F, Verrier ED. Schwannoma of the left atrium: diagnostic evaluation and surgical resection. Ann Thorac Surg. 1994;57:743–6. - PubMed

Publication types

LinkOut - more resources