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. 2014 Oct;31(10):215.
doi: 10.1007/s12032-014-0215-1. Epub 2014 Sep 11.

Is there any effect of lower extremity deep vein thrombosis which proven by Doppler ultrasonography on cancer recurrence in patients with stage III colon cancer? A study of the Turkish Descriptive Oncological Researches Group

Ozgur Tanriverdi  1 , Birdal Yildirim, Suha Gul, Esin Cevik, Tulay Akman, Suna Cokmert, Kezban Nur Pilanci, Nilufer Avci, Cetin Ordu, Sabri Barutca
Affiliations

Is there any effect of lower extremity deep vein thrombosis which proven by Doppler ultrasonography on cancer recurrence in patients with stage III colon cancer? A study of the Turkish Descriptive Oncological Researches Group

Ozgur Tanriverdi et al. Med Oncol. 2014 Oct.

Abstract

This study aimed to determine the predictive value of lower extremity deep vein thrombosis (LE-DVT) on first cancer recurrence in patients with stage III colon cancer. A total of 113 eligible patients with stage III colon cancer were divided into two groups according to whether they had LE-DVT. LE-DVT was detected in 29 (26%) patients. Presence of recurrence with distant metastasis had a significant positive correlation with baseline platelet count, baseline mean platelet volume, and the presence of lower extremity deep vein thrombosis. It was concluded that the relation between disease progression and the presence of LE-DVT in stage III colon cancer is independent of other study variables (P=0.031; OR=4.27; 95% CI 1.89-6.71). We hypothesized that the presence of LE-DVT in patients with stage III colon cancer may predict to early cancer recurrence with distant metastasis.

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