Case Reports

. 2014 Oct 14;83(16):1478-80.

doi: 10.1212/WNL.0000000000000880. Epub 2014 Sep 10.

Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib

Ahmed Idbaih¹, Karima Mokhtari², Jean-François Emile², Damien Galanaud², Hayat Belaid², Simon de Bernard², Neila Benameur², Vlad-Ciprian Barlog², Dimitri Psimaras², Jean Donadieu², Catherine Carpentier², Nadine Martin-Duverneuil², Julien Haroche², Loic Feuvret², Noel Zahr², Jean-Yves Delattre², Khê Hoang-Xuan²

Affiliations

¹ From the Université Pierre et Marie Curie-Paris 6 (A.I., K.M., C.C., J.-Y.D., K.H.-X.), Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière (CRICM), UMRS 975; Inserm U 975 (A.I., K.M., C.C., J.-Y.D., K.H.-X.); CNRS (A.I., K.M., C.C., J.-Y.D., K.H.-X.), UMR 7225; AP-HP (A.I., K.M., D.G., H.B., N.B., V.-C.B., D.P., N.M.-D., J.H., L.F., N.Z., J.-Y.D., K.H.-X.), Groupe Hospitalier Pitié-Salpêtrière, Paris; Versailles University & Ambroise Paré Hospital (J.-F.E.), AP-HP, Boulogne; AltraBio (S.d.B.), Lyon; and AP-HP (J.D.), Hôpital Trousseau, Paris, France. ahmed.idbaih@psl.aphp.fr.
² From the Université Pierre et Marie Curie-Paris 6 (A.I., K.M., C.C., J.-Y.D., K.H.-X.), Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière (CRICM), UMRS 975; Inserm U 975 (A.I., K.M., C.C., J.-Y.D., K.H.-X.); CNRS (A.I., K.M., C.C., J.-Y.D., K.H.-X.), UMR 7225; AP-HP (A.I., K.M., D.G., H.B., N.B., V.-C.B., D.P., N.M.-D., J.H., L.F., N.Z., J.-Y.D., K.H.-X.), Groupe Hospitalier Pitié-Salpêtrière, Paris; Versailles University & Ambroise Paré Hospital (J.-F.E.), AP-HP, Boulogne; AltraBio (S.d.B.), Lyon; and AP-HP (J.D.), Hôpital Trousseau, Paris, France.

PMID: 25209580
DOI: 10.1212/WNL.0000000000000880

Case Reports

Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib

Ahmed Idbaih et al. Neurology. 2014.

. 2014 Oct 14;83(16):1478-80.

doi: 10.1212/WNL.0000000000000880. Epub 2014 Sep 10.

Authors

Affiliations

¹ From the Université Pierre et Marie Curie-Paris 6 (A.I., K.M., C.C., J.-Y.D., K.H.-X.), Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière (CRICM), UMRS 975; Inserm U 975 (A.I., K.M., C.C., J.-Y.D., K.H.-X.); CNRS (A.I., K.M., C.C., J.-Y.D., K.H.-X.), UMR 7225; AP-HP (A.I., K.M., D.G., H.B., N.B., V.-C.B., D.P., N.M.-D., J.H., L.F., N.Z., J.-Y.D., K.H.-X.), Groupe Hospitalier Pitié-Salpêtrière, Paris; Versailles University & Ambroise Paré Hospital (J.-F.E.), AP-HP, Boulogne; AltraBio (S.d.B.), Lyon; and AP-HP (J.D.), Hôpital Trousseau, Paris, France. ahmed.idbaih@psl.aphp.fr.
² From the Université Pierre et Marie Curie-Paris 6 (A.I., K.M., C.C., J.-Y.D., K.H.-X.), Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière (CRICM), UMRS 975; Inserm U 975 (A.I., K.M., C.C., J.-Y.D., K.H.-X.); CNRS (A.I., K.M., C.C., J.-Y.D., K.H.-X.), UMR 7225; AP-HP (A.I., K.M., D.G., H.B., N.B., V.-C.B., D.P., N.M.-D., J.H., L.F., N.Z., J.-Y.D., K.H.-X.), Groupe Hospitalier Pitié-Salpêtrière, Paris; Versailles University & Ambroise Paré Hospital (J.-F.E.), AP-HP, Boulogne; AltraBio (S.d.B.), Lyon; and AP-HP (J.D.), Hôpital Trousseau, Paris, France.

PMID: 25209580
DOI: 10.1212/WNL.0000000000000880

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Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib

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Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib

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