Schizophrenia: overview and treatment options
Abstract
Schizophrenia is a complex disorder characterized by an array of symptoms. This heterogeneity has resulted in a lack of consensus regarding diagnostic criteria, etiology, and pathophysiology, and has complicated efforts to devise effective treatments.
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References
-
- Lavretsky H. History of Schizophrenia as a Psychiatric Disorder. In: Mueser KT, Jeste DV, editors. Clinical Handbook of Schizophrenia. New York, New York: Guilford Press; 2008. pp. 3–12.
-
- Crismon L, Argo TR, Buckley PF. Schizophrenia. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. 1Pharmacotherapy: A Pathophysiologic Approach. 9th ed. New York, New York: McGraw-Hill; 2014. pp. 1019–1046.
-
- Beck AT, Rector NA, Stolar N, Grant P. Schizophrenia: Cognitive Theory, Research, and Therapy. New York, New York: Guilford Press; 2009. Biological Contributions; pp. 30–61.
-
- Schwartz JH, Javitch JA. Neurotransmitters. In: Kandel ER, Schwartz JH, Jessell TM, et al., editors. Principles of Neural Science. 5th ed. New York, New York: McGraw-Hill; 2013. pp. 289–305.
-
- Stahl SM. Psychosis and Schizophrenia. In: Stahl SM, editor. Essential Psychopharmacology: Neuroscientific Basis and Practical Applications. 2nd ed. Cambridge, United Kingdom: Cambridge University Press; 2000. pp. 365–399.
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