Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Jan;5(4):241-4.
Epub 2012 Mar 20.

Comparison of complications of chorionic villus sampling and amniocentesis

Nahid Shahbazian  1 , Mojgan Barati  1 , Parvin Arian  2 , Najmie Saadati  1
Affiliations

Comparison of complications of chorionic villus sampling and amniocentesis

Nahid Shahbazian et al. Int J Fertil Steril. 2012 Jan.

Abstract

Background: A significant number of pregnancies are associated with the cytogenetic abnormalities of the fetus. Amniocentesis and chorionic villus sampling (CVS) are procedures used for prenatal genetic diagnosis. In this study, we compare the safety and complications of mid-trimester amniocentesis and transabdominal CVS.

Materials and methods: This analytic cross-sectional study was performed in 308 patients from 2.11.2007 to 26.10.2009. We had 155 cases of amniocentesis, which we performed in weeks 15-23 of pregnancy; and 153 cases of CVS, which we performed during weeks 10-14 of pregnancy.

Results: There were 2 cases (1.2%) of premature rupture of membrane (PROM) in amniocentesis which occurred 1 and 10 days after the procedure and caused pregnancy loss before 20 weeks. We had 1 case (0.7%) of abortion in CVS, which occurred 10 days after the procedure. Additionally, there was 1 case of amniotic fluid leakage (0.7%) in which, after admission to the hospital and observation, leakage was stopped and the pregnancy continued normally.

Conclusion: In this study, we had more complications with amniocentesis cases than CVS. CVS is a procedure performed in the earlier stages of pregnancy and its complications are less than amniocentesis. We suggest CVS to be the procedure of choice for genetic diagnosis.

Keywords: Amniocentesis; Chorionic Villus Sampling; Complications; Genetic Testing.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Benn PA, Egan JF, Fang M, Smith- Bindman R. Changes in the utilization of prenatal diagnosis. Obstet Gynecol. 2004;103(6):1255–1260. - PubMed
    1. Smith GCS. Delivery after pervious cesarean section. In: James DK, Steer PJ, Weiner CP, Gonic B, editors. High risk pregnancy: management options. 3rd ed. New Dehli: Elsevier; 2006. pp. 209–215.
    1. Tahmaspour AR. First trimester screening for chromosomal Anomaly. Yakhteh. 2009;11(Suppl 1)
    1. Cunningham FG, Leveno KL, Bloom SL, Hauth JC, Rouse D, Spong C. Williams Obstetrics. 23rd ed. New York, NY: McGraw Hill; 2010. pp. 299–301.
    1. Cunnigham FG, Leveno KJ, Bloom SL, Hauth JC, Gilstrap II LC, Wenstrom KD. Williams Obstetrics. 22nd ed. New York, NY: McGraW Hill; 2005. pp. 328–330.

LinkOut - more resources