Tethering viral restriction to signal transduction
- PMID: 25211067
- DOI: 10.1016/j.chom.2014.08.013
Tethering viral restriction to signal transduction
Abstract
Tetherin serves as an innate sensor of viral infection in addition to its role in inhibiting virus release from infected cells. In this issue, Galão et al. (2014) provide important insights into the mechanism of virus-induced signal transduction by tetherin.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Retroviral retention activates a Syk-dependent HemITAM in human tetherin.Cell Host Microbe. 2014 Sep 10;16(3):291-303. doi: 10.1016/j.chom.2014.08.005. Cell Host Microbe. 2014. PMID: 25211072 Free PMC article.
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