Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Sep 15;128(2):348-57.
doi: 10.1016/j.foodchem.2011.03.030. Epub 2011 Mar 12.

New and bioactive lignans from the fruits of Schisandra sphenanthera

Hsin-Chan Huang  1 , Yu-Chi Lin  1 , Ahmed Eid Fazary  1 , I-Wen Lo  1 , Chia-Ching Liaw  1 , Yi-Zsau Huang  2 , Shorong-Shii Liou  3 , Ya-Ching Shen  4
Affiliations

New and bioactive lignans from the fruits of Schisandra sphenanthera

Hsin-Chan Huang et al. Food Chem. .

Abstract

Phytochemical investigation of the ethanol extract from the fruits of Schisandra sphenanthera has resulted in isolation of seven new oxygenated lignans (1-7), in addition to 11 known compounds (8-18). Their structures were determined on the basis of 2D-NMR (COSY, HMQC, HMBC and NOESY) analyses. The isolated components were evaluated with a reporter gene assay that measures their anti-liver fibrosis activity. Compounds 1, 2, 4, 11, 13, 14 and 18 exhibited significant anti-inflammatory activity on HSC-T6 test.

Keywords: Anti-liver fibrosis activity; Aryltetralone lignans; Dibenzocyclooctadienes; Schisandra sphenanthera.

PubMed Disclaimer

LinkOut - more resources