Practical Implementation of the 2013 AHA/ACC Blood Cholesterol Guidelines
- PMID: 25212817
- PMCID: PMC4352137
- DOI: 10.1007/s11936-014-0347-9
Practical Implementation of the 2013 AHA/ACC Blood Cholesterol Guidelines
Abstract
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in the United States. Choosing the appropriate patients for whom to initiate statin therapy to reduce the risk of ASCVD is of paramount importance. The new AHA/ACC guidelines on the treatment of cholesterol emphasize a patient-centered approach that shifts away from arbitrary LDL-C goals and recommends targeting statin therapy in patient populations that show ASCVD risk-reduction benefit. In addition, the guidelines emphasize lifestyle modification and the importance of the clinician-patient relationship in discussing ASCVD risk and initiating statin therapy.
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References
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Mihaylova B, Emberson J, Blackwell L, Cholesterol Treatment Trialists’ (CTT) Collaborators et al. The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet. 2012;380(9841):581–90. One of the key meta-analyses on which the new cholesterol guidelines are based.
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Taylor F, Huffman MD, Macedo AF, et al. Statins for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2013;1(1):CD004816. doi:10.1002/14651858. CD14004816.pub14651855. One of the key meta-analyses on which the new cholesterol guidelines are based.
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Stone NJ, Robinson JG, Lichtenstein AH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults [published online November 12, 2013] Circulation. 2013 doi:10.1161/01.cir.0000437738.63853.7a. The new cholesterol guidelines in detail.
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