An update on the impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: effect modification by risk of bronchopulmonary dysplasia

Lex W Doyle¹, Henry L Halliday², Richard A Ehrenkranz³, Peter G Davis⁴, John C Sinclair⁵

Affiliations

¹ Department of Obstetrics and Gynecology, The Royal Women's Hospital and University of Melbourne, Parkville, Australia; Clinical Sciences, Murdoch Children's Research Center, Parkville, Australia. Electronic address: lwd@unimelb.edu.au.
² Department of Child Health, Queen's University, Belfast, Northern Ireland.
³ Department of Pediatrics, Yale University School of Medicine, New Haven, CT.
⁴ Department of Obstetrics and Gynecology, The Royal Women's Hospital and University of Melbourne, Parkville, Australia; Clinical Sciences, Murdoch Children's Research Center, Parkville, Australia.
⁵ Emeritus, Departments of Pediatrics, Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

PMID: 25217197
DOI: 10.1016/j.jpeds.2014.07.049

An update on the impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: effect modification by risk of bronchopulmonary dysplasia

Lex W Doyle et al. J Pediatr. 2014 Dec.

. 2014 Dec;165(6):1258-60.

doi: 10.1016/j.jpeds.2014.07.049. Epub 2014 Sep 10.

Authors

Lex W Doyle¹, Henry L Halliday², Richard A Ehrenkranz³, Peter G Davis⁴, John C Sinclair⁵

Affiliations

¹ Department of Obstetrics and Gynecology, The Royal Women's Hospital and University of Melbourne, Parkville, Australia; Clinical Sciences, Murdoch Children's Research Center, Parkville, Australia. Electronic address: lwd@unimelb.edu.au.
² Department of Child Health, Queen's University, Belfast, Northern Ireland.
³ Department of Pediatrics, Yale University School of Medicine, New Haven, CT.
⁴ Department of Obstetrics and Gynecology, The Royal Women's Hospital and University of Melbourne, Parkville, Australia; Clinical Sciences, Murdoch Children's Research Center, Parkville, Australia.
⁵ Emeritus, Departments of Pediatrics, Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

PMID: 25217197
DOI: 10.1016/j.jpeds.2014.07.049

Abstract

Infants at higher risk of bronchopulmonary dysplasia had increased rates of survival free of cerebral palsy after postnatal corticosteroid treatment in a previous metaregression of data from 14 randomized controlled trials. The relationship persists and is stronger in an updated analysis with data from 20 randomized controlled trials.

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An update on the impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: effect modification by risk of bronchopulmonary dysplasia

Affiliations

An update on the impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: effect modification by risk of bronchopulmonary dysplasia

Authors

Affiliations

Abstract

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical