Comment

. 2014 Nov;69(11):1049-50.

doi: 10.1136/thoraxjnl-2014-206188. Epub 2014 Sep 12.

Location, location, location: studying anatomically comparable airways is highly relevant to understanding COPD

Benjamin M Smith¹, Eric A Hoffman², Stephen Rennard³, R Graham Barr⁴

Affiliations

¹ Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA Department of Medicine, McGill University, Montreal, Quebec, Canada.
² Departments of Radiology, Medicine and Biomedical Engineering, University of Iowa, Iowa City, Iowa, USA.
³ Department of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
⁴ Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.

PMID: 25217475
PMCID: PMC6291196
DOI: 10.1136/thoraxjnl-2014-206188

Comment

Location, location, location: studying anatomically comparable airways is highly relevant to understanding COPD

Benjamin M Smith et al. Thorax. 2014 Nov.

. 2014 Nov;69(11):1049-50.

doi: 10.1136/thoraxjnl-2014-206188. Epub 2014 Sep 12.

Authors

Benjamin M Smith¹, Eric A Hoffman², Stephen Rennard³, R Graham Barr⁴

Affiliations

¹ Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA Department of Medicine, McGill University, Montreal, Quebec, Canada.
² Departments of Radiology, Medicine and Biomedical Engineering, University of Iowa, Iowa City, Iowa, USA.
³ Department of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
⁴ Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.

PMID: 25217475
PMCID: PMC6291196
DOI: 10.1136/thoraxjnl-2014-206188

No abstract available

Keywords: Airway Epithelium; COPD epidemiology; Imaging/CT MRI etc.

PubMed Disclaimer

Conflict of interest statement

Competing interests EAF is a founder and share holder of VIDA Diagnostics, a company that is commercialising pulmonary image analysis software developed, in part, at the University of Iowa.

Comment on

Is the 'spatially matched central airways' relevant to studies of airway dimensions in COPD?
Nakano Y, Tho NV, Coxson HO. Nakano Y, et al. Thorax. 2014 Nov;69(11):1048-9. doi: 10.1136/thoraxjnl-2014-206118. Epub 2014 Sep 5. Thorax. 2014. PMID: 25192710 No abstract available.

Cited by

Pulmonary CT and MRI phenotypes that help explain chronic pulmonary obstruction disease pathophysiology and outcomes.
Hoffman EA, Lynch DA, Barr RG, van Beek EJ, Parraga G; IWPFI Investigators. Hoffman EA, et al. J Magn Reson Imaging. 2016 Mar;43(3):544-57. doi: 10.1002/jmri.25010. Epub 2015 Jul 22. J Magn Reson Imaging. 2016. PMID: 26199216 Free PMC article. Review.

References

1. Nakano Y, Tho NV, Coxson HO. Is the ‘spatially matched central airways’ relevant to studies of airway dimensions in COPD? Thorax 2014;69:1048–9. - PubMed
1. Smith BM, Hoffman EA, Rabinowitz D, et al. Comparison of spatially matched airways reveals thinner airway walls in COPD. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study and the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Thorax 2014;69:987–96. - PMC - PubMed
1. Hsia CC, Hyde DM, Ochs M, et al. An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure. Am J Respir Crit Care Med 2010;181:394–418. - PMC - PubMed
1. Weibel ER. Morphometry of the human lung. Berlin: Springer, 1963.
1. McDonough JE, Yuan R, Suzuki M, et al. Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N Engl J Med 2011;365:1567–75. - PMC - PubMed

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Location, location, location: studying anatomically comparable airways is highly relevant to understanding COPD

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Location, location, location: studying anatomically comparable airways is highly relevant to understanding COPD

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