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Randomized Controlled Trial
. 2014 Nov 1:144:87-92.
doi: 10.1016/j.drugalcdep.2014.08.013. Epub 2014 Aug 29.

Pain is associated with risky drinking over time among HIV-infected persons in St. Petersburg, Russia

Judith I Tsui  1 , Debbie M Cheng  2 , Sharon M Coleman  3 , Marlene C Lira  4 , Elena Blokhina  5 , Carly Bridden  4 , Evgeny Krupitsky  6 , Jeffrey H Samet  7
Affiliations
Randomized Controlled Trial

Pain is associated with risky drinking over time among HIV-infected persons in St. Petersburg, Russia

Judith I Tsui et al. Drug Alcohol Depend. .

Abstract

Background: Pain is highly prevalent among persons with HIV. Alcohol may be used to "self-medicate" pain. This study examined the association between pain and risky alcohol use over time in a cohort of HIV-infected Russian drinkers.

Methods: This secondary analysis utilized longitudinal data from a randomized trial of a behavioral intervention. Subjects included HIV-infected adults who reported past 6-month risky drinking and unprotected sex and were recruited from HIV and addiction treatment sites in St. Petersburg, Russia. The main independent variable was pain that at least moderately interfered with daily living. The primary outcome was past month risky drinking amounts based on NIAAA guidelines. General estimating equations (GEE) logistic regression models were used to calculate odds ratios and 95% confidence intervals for the association between pain and risky drinking over time (i.e., baseline, 6 and 12 months), adjusting for potential confounders.

Results: Baseline characteristics of participants (n=699) were mean age of 30 (SD ±5) years, 41% female, and 22% <9th grade education. Nearly one quarter (24%) had a CD4 cell count <200 cells/μl, and only 17% were on antiretroviral therapy. Nearly half (46%) reported at least moderate pain interference in the past month and 81% were drinking risky amounts. In adjusted longitudinal GEE models, pain was significantly associated with greater odds of reporting past month risky drinking (AOR = 1.34, 95% CI: 1.05-1.71, p value=0.02).

Conclusions: Among a cohort of HIV-infected Russian drinkers, pain that at least moderately interfered with daily living was associated with higher odds of reporting risky drinking amounts over time.

Keywords: HIV; Pain; Risky alcohol use; Russia.

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References

    1. Arnsten JH, Demas PA, Grant RW, Gourevitch MN, Farzadegan H, Howard AA, Schoenbaum EE. Impact of active drug use on antiretroviral therapy adherence and viral suppression in HIV-infected drug users. J. Gen. Intern. Med. 2002;17:377–381. - PMC - PubMed
    1. Azar MM, Springer SA, Meyer JP, Altice FL. A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization. Drug Alcohol Depend. 2010;112:178–193. - PMC - PubMed
    1. Beck AT. Russian translation copyright 2007. Pearson Education, Inc.; San Antonio, TX: 1996. Beck Depression Inventory - Second Edition.
    1. Berg KM, Cooperman NA, Newville H, Arnsten JH. Self-efficacy and depression as mediators of the relationship between pain and antiretroviral adherence. AIDS Care. 2009;21:244–248. - PMC - PubMed
    1. Bhattacharya R, Shuhart MC. Hepatitis C and alcohol: interactions, outcomes, and implications. J. Clin. Gastroenterol. 2003;36:242–252. - PubMed

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