Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2014 Nov;71(11):1357-8.
doi: 10.1001/jamaneurol.2014.2462.

Preclinical biomarkers in Alzheimer disease: a sum greater than the parts

Susan M Resnick  1
Affiliations
Editorial

Preclinical biomarkers in Alzheimer disease: a sum greater than the parts

Susan M Resnick. JAMA Neurol. 2014 Nov.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Comment on

References

    1. Sperling RA, Rentz DM, Johnson KA, et al. The A4 study: stopping AD before symptoms begin? Sci Transl Med. 2014;6(228):228fs213. doi: 10.1126/scitranslmed.3007941. - DOI - PMC - PubMed
    1. Mormino EC, Betensky RA, Hedden T, et al. Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals [published online September 15, 2014] JAMA Neurol. doi: 10.1001/jamaneurol.2014.2031. - DOI - PMC - PubMed
    1. Sperling RA, Aisen PS, Beckett LA, et al. Toward defining the preclinical stages of Alzheimer’s disease: recommendations from the National Institute on Aging–Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement. 2011;7(3):280–292. - PMC - PubMed
    1. Jack CR, Jr, Knopman DS, Weigand SD, et al. An operational approach to National Institute on Aging–Alzheimer’s Association criteria for preclinical Alzheimer disease. Ann Neurol. 2012;71(6):765–775. - PMC - PubMed
    1. Jack CR, Jr, Knopman DS, Jagust WJ, et al. Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade. Lancet Neurol. 2010;9(1):119–128. - PMC - PubMed

Substances