Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Sep;30(5):1141-2.
doi: 10.12669/pjms.305.5491.

A rare case of pituitrin-induced delayed encephalopathy

Tingting Xu  1 , Lijun Zhu  2 , Jiachun Feng  3 , Shaokuan Feng  4
Affiliations
Case Reports

A rare case of pituitrin-induced delayed encephalopathy

Tingting Xu et al. Pak J Med Sci. 2014 Sep.

Abstract

A 26-year-old girl was admitted to the Neurological Department of The First Teaching Hospital of Jilin University with complaints of rapidly deteriorating speech clumsiness for 18 days. Five Days before her attack she had undergone intramuscular pituitrin therapy on account of recurrent haemoptysis. Cranial MRI revealed multiple abnormal signals in bilateral hemisphere and symmetric abnormal signal in bilateral caudate nucleus and putamen. Serum electrolyte analysis revealed mild hyponatremia. The abnormal signals in bilateral hemisphere almost disappeared after 7 days of cerebral circulation ameliorating and serum electrolyte turbulence correcting therapy, whereas the symmetric abnormal signals in bilateral caudate nucleus and putamen still existed. A diagnosis of delayed encephalopathy was made and we presume the encephalopathy was associated with pituitrin therapy.

Keywords: Delayed encephalopathy; Hyponatremia; Pituitrin.

PubMed Disclaimer

Figures

Fig.1
Fig.1
DWI (2013-05-31) showed multiple abnormal signals in bilateral hemisphere and symmetric abnormal signal in bilateral caudate nucleus and putamen
Fig.2
Fig.2
DWI (2013-06-07) showed symmetric abnormal signals in bilateral caudate nucleus and putamen
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Lose G, Mattiasson A, Walter S, Lalos O, van Kerrebroeck P, Abrams P, et al. Clinical experiences with desmopressin for long-term treatment of nocturia. J Urol. 2004;172(3):1021–1025. - PubMed
    1. Kim RJ, Malattia C, Allen M, Moshang T Jr, Maghnie M. Vasopressin and desmopressin in central diabetes insipidus: adverse effects and clinical considerations. Pediatr Endocrinol Rev. 2004;2(Suppl 1):115–123. - PubMed
    1. Ragoschke-Schumm A, Witte OW, Terborg C. Hyponatremic encephalopathy caused by desmopressin-induced hyponatremia. J Neurol. 2005;252(11):1411–1413. - PubMed
    1. Sun I, Sun A, Gercek A, Kilic T. Desmopressin-induced hypertension as a rare cause of hypertensive encephalopathy. J Neurosurg Anesthesiol. 2007;19(4):289–290. - PubMed
    1. Delmas A, Leone M, Rousseau S, Albanèse J, Martin C. Vasopressin and terlipressin in septic shock patients. Critical Care. 2005;9(2):212–222. - PMC - PubMed

Publication types

LinkOut - more resources