Update on the Epidemiology, Treatment, and Outcomes of Carbapenem-resistant Acinetobacter infections
- PMID: 25229014
- PMCID: PMC4161759
- DOI: 10.4068/cmj.2014.50.2.37
Update on the Epidemiology, Treatment, and Outcomes of Carbapenem-resistant Acinetobacter infections
Abstract
Carbapenem-resistant Acinetobacter species are increasingly recognized as major nosocomial pathogens, especially in patients with critical illnesses or in intensive care. The ability of these organisms to accumulate diverse mechanisms of resistance limits the available therapeutic agents, makes the infection difficult to treat, and is associated with a greater risk of death. In this review, we provide an update on the epidemiology, resistance mechanisms, infection control measures, treatment, and outcomes of carbapenem-resistant Acinetobacter infections.
Keywords: Acinetobacter baumannii; Colistin; Drug therapy.
Conflict of interest statement
None declared.
Figures
References
-
- Fournier PE, Richet H. The epidemiology and control of Acinetobacter baumannii in health care facilities. Clin Infect Dis. 2006;42:692–699. - PubMed
-
- Euzéby JP. List of bacterial names with standing in nomenclature: a folder available on the internet. Int J Syst Bacteriol. 1997;47:590–592. - PubMed
-
- Tomaras AP, Dorsey CW, Edelmann RE, Actis LA. Attachment to and biofilm formation on abiotic surfaces by Acinetobacter baumannii: involvement of a novel chaperone-usher pili assembly system. Microbiology. 2003;149:3473–3484. - PubMed
-
- Choi CH, Lee EY, Lee YC, Park TI, Kim HJ, Hyun SH, et al. Outer membrane protein 38 of Acinetobacter baumannii localizes to the mitochondria and induces apoptosis of epithelial cells. Cell Microbiol. 2005;7:1127–1138. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
