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Review
. 2014 Sep 5;4(1):1-6.
eCollection 2014.

Renal complications of beta-thalassemia major in children

Ashraf Bakr  1 , Youssef Al-Tonbary  2 , Ghada Osman  3 , Rasha El-Ashry  2
Affiliations
Review

Renal complications of beta-thalassemia major in children

Ashraf Bakr et al. Am J Blood Res. .

Abstract

The success that has been made in the care of patients with thalassemia has led to the emergence of unrecognized complications including several renal abnormalities. Chronic anemia and iron overload as well as the use of iron chelator are believed to lie behind these abnormalities. Many investigators document the presence of tubular dysfunction and abnormalities in glomerular filtration rate in these patients. In this review we will discuss the updates in the diagnosis, pathogenesis and prevention of renal complications of thalassemia.

Keywords: Children; renal complications; thalassemia.

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