Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jun;32(3):188-93.
doi: 10.1097/WNP.0000000000000133.

Seizures and brain regulatory systems: consciousness, sleep, and autonomic systems

Madineh Sedigh-Sarvestani  1 , Hal Blumenfeld, Tobias Loddenkemper, Lisa M Bateman
Affiliations
Review

Seizures and brain regulatory systems: consciousness, sleep, and autonomic systems

Madineh Sedigh-Sarvestani et al. J Clin Neurophysiol. 2015 Jun.

Abstract

Research into the physiologic underpinnings of epilepsy has revealed reciprocal relationships between seizures and the activity of several regulatory systems in the brain. This review highlights recent progress in understanding and using the relationships between seizures and the arousal or consciousness system, the sleep-wake and associated circadian system, and the central autonomic network.

PubMed Disclaimer

References

    1. Archer JS, Abbott DF, Waites AB, Jackson GD. fMRI “deactivation” of the posterior cingulate during generalized spike and wave. Neuroimage. 2003;20(4):1915–22. - PubMed
    1. Arthuis M, Valton L, Regis J, Chauvel P, Wendling F, Naccache L, Bernard C, Bartolomei F. Impaired consciousness during temporal lobe seizures is related to increased long-distance cortical-subcortical synchronization. Brain. 2009;132(Pt 8):2091–101. - PubMed
    1. Bai X, Vestal M, Berman R, Negishi M, Spann M, Vega C, Desalvo M, Novotny EJ, Constable RT, Blumenfeld H. Dynamic time course of typical childhood absence seizures: EEG, behavior, and functional magnetic resonance imaging. J Neurosci. 2010;30:5884–93. - PMC - PubMed
    1. Bartolomei F, McGonigal A, Naccache L. Alternation of consciousness in focal epilepsy: the global workspace alteration theory. Epilepsy Behav. 2014;30:17–23. - PubMed
    1. Bateman LM, Li CS, Seyal M. Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors. Brain. 2008;131(Pt 12):3239–45. - PMC - PubMed