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. 2015 Feb 15;211(4):558-62.
doi: 10.1093/infdis/jiu503. Epub 2014 Sep 18.

Protection against gastroenteritis in US households with children who received rotavirus vaccine

Margaret M Cortese  1 , Rebecca Moritz Dahl  1 , Aaron T Curns  1 , Umesh D Parashar  1
Affiliations

Protection against gastroenteritis in US households with children who received rotavirus vaccine

Margaret M Cortese et al. J Infect Dis. .

Abstract

We used Truven Health Marketscan claims database (2008-2011) to compare gastroenteritis rates during January-June among households whose child had received rotavirus vaccine with those whose child did not receive vaccine. Statistically significantly lower rates of hospitalization with a rotavirus gastroenteritis or unspecified-gastroenteritis discharge code occurred in vaccinated households among persons 20-29 years and females 20-29 years (2008/2009), and males 30-39 years (2009/2010). Lower emergency department gastroenteritis rates occurred in vaccinated households among females 20-29 years (2009/2010) and individuals 5-19 years (2010/2011). These data suggest rotavirus vaccination of infants provides indirect protection against moderate-to-severe rotavirus disease in young parents and older siblings.

Keywords: adults; diarrhea; gastroenteritis; household; immunization; indirect protection; rotavirus; rotavirus vaccine.

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