Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Spring;13(2):559-66.

Total Phenolic Content and Antibacterial Activity of Five Plants of Labiatae against Four Foodborne and Some Other Bacteria

Arash Mahboubi  1 , Mohammad Kamalinejad  2 , Abdul Majid Ayatollahi  3 , Mohammad Babaeian  2
Affiliations

Total Phenolic Content and Antibacterial Activity of Five Plants of Labiatae against Four Foodborne and Some Other Bacteria

Arash Mahboubi et al. Iran J Pharm Res. 2014 Spring.

Abstract

The aim of this study was to evaluate the antibacterial effects of Thymus vulgaris, Thymus caramanicus, Zataria multiflora, Ziziphora clinopodioides and Ziziphora tenuior against four foodborne and four other bacteria including Staphylococcus aureus, Shigella dysenteriae, Salmonella typhimurium, Escherichia coli, Staphylococcus epidermidis, Bacillus subtilis, MRSA and Pseudomona aeruginosa and measuring the amount of total phenolics of the plants. The extracts were prepared by maceration method. Pre-evaluation of the antimicrobial effect was utilized by cup-plate technique and then Minimum Inhibitory Concentration was determined by agar dilution method according to NCCLS. The total phenolics as a possible cause of antibacterial effect, was measured by Folin-Ciocalteucolorimetry. The results showed that T. caramanicus and Z. multiflora were the most effective ones with MIC values between 0.78-3.125 mg/mL against all of the Bactria and Z. tenuior and Z. clinopodioides had the minimum antimicrobial activity. Total phenolic contents of these five plants were different and followed the general pattern of the antimicrobial effect. The antibacterial effects and the total phenolic content of T. caramanicus and Z. multiflora were remarkable and should be investigated more in future studies.

Keywords: Antibacterial; Folin-Ciocalteu; Foodborne; Phenolic content; Thymus; Zataria; Ziziphora.

PubMed Disclaimer

Figures

Figure 1
Figure 1
The minimum inhibitory concentration (MIC) of extracts in defferent bacterial species
See this image and copyright information in PMC

References

    1. Salek Moghadam A, Forouhesh Tehrani H, Mozafari N, Ansari H. Prevalence of virulence factors among E coli isolated from food materials from Iran University of Medical Sciences' food microbial laboratory. Kaums. J. FEYZ. 2000;4:32–40.
    1. García S, Heredia N. Microbiologically Safe Foods. New York : John Wiley & Sons Inc; 2009. Foodborne Pathogens and Toxins: An Overview; p. 32.
    1. Zendehdel M, Babapour V. Study of antinociceptive effects of Ziziphora tenuior and its interference on opioidergic and serotoninergic systems. J. Vet. Res. 2010;65:57–60.
    1. Wesley I. Microbiologically Safe Foods. New York : John Wiley & Sons Inc; 2009. Public Health Impact of Foodborne Illness: Impetus for the International Food Safety Effort; p. 83.
    1. WHO Media Centre. Diarrhoeal disease, Fact sheet N330. 2013. [[cited 2013 Jan 5]]. Available from: URL: http://www.who.int/mediacentre/factsheets/fs330/en/index.html.

LinkOut - more resources