Love is in the Aire: mTECs share their assets
- PMID: 25238088
- DOI: 10.1016/j.immuni.2014.08.013
Love is in the Aire: mTECs share their assets
Abstract
Self-tolerance imposition requires the presentation of self-antigens by a variety of thymic antigen-presenting cells. In this issue of Immunity, Perry et al. (2014) reveal unidirectional self-antigen transfer from medullary thymic epithelial cells to dendritic cells as an essential aspect.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
-
Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus.Immunity. 2014 Sep 18;41(3):414-426. doi: 10.1016/j.immuni.2014.08.007. Epub 2014 Sep 11. Immunity. 2014. PMID: 25220213 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources