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Comparative Study
. 1989 May;42(5):761-8.
doi: 10.7164/antibiotics.42.761.

Mechanism of activation of the antitumor antibiotic neocarzinostatin by mercaptan and sodium borohydride

O D Hensens  1 , I H Goldberg
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Free article
Comparative Study

Mechanism of activation of the antitumor antibiotic neocarzinostatin by mercaptan and sodium borohydride

O D Hensens et al. J Antibiot (Tokyo). 1989 May.
Free article

Abstract

The structures of mercaptan and sodium borohydride reaction products of neocarzinostatin chromophore A (NCS Chrom A) are compared. Implications on the mechanism of activation of NCS are discussed.

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