Malaria prevention during pregnancy-is there a next step forward?
- PMID: 25247816
- PMCID: PMC4172429
- DOI: 10.1371/journal.pmed.1001734
Malaria prevention during pregnancy-is there a next step forward?
Abstract
Richard Steketee discusses the two studies by Clara Menendez and colleagues that describe using mefloquine for the intermittent preventative therapy of malaria in both HIV positive and HIV negative pregnant women and outlines the next steps.
Please see later in the article for the Editors' Summary
Conflict of interest statement
I declare that I have no competing interests related to the article.
Comment on
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Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-negative women: a multicentre randomized controlled trial.PLoS Med. 2014 Sep 23;11(9):e1001733. doi: 10.1371/journal.pmed.1001733. eCollection 2014 Sep. PLoS Med. 2014. PMID: 25247709 Free PMC article. Clinical Trial.
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Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-infected women receiving cotrimoxazole prophylaxis: a multicenter randomized placebo-controlled trial.PLoS Med. 2014 Sep 23;11(9):e1001735. doi: 10.1371/journal.pmed.1001735. eCollection 2014 Sep. PLoS Med. 2014. PMID: 25247995 Free PMC article. Clinical Trial.
References
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- Wickramasuriya GAW (1935) Some observations on malaria occuring in association with pregnancy. With special reference to the transplacental passage of parasites from the maternal to the foetal circulation. Br J Obstet Gynaecol 42: 816–834.
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- Steketee RW, Wirima JJ, Bloland PB, Chilima B, Mermin JH, et al. (1996) Impairment of a pregnant woman's acquired ability to limit Plasmodium falciparum by infection with human immunodeficiency virus type-1. Am J Trop Med Hyg55 (suppl 1)42–49. - PubMed
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- ter Kuile FO, Parise ME, Verhoeff FH, Udhayakumar V, Newman RD, et al. (2004) The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-saharan Africa. Am J Trop Med Hyg 71: 41–54. - PubMed
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