Protracted fecal shedding of HEV during ribavirin therapy predicts treatment relapse
- PMID: 25249523
- DOI: 10.1093/cid/ciu742
Protracted fecal shedding of HEV during ribavirin therapy predicts treatment relapse
Abstract
Twenty-four solid-organ-transplant recipients with chronic hepatitis E virus (HEV) infections were given ribavirin therapy for 3 months. All the patients with protracted fecal HEV shedding during treatment suffered a relapse. Monitoring HEV fecal excretion could be used to determine the optimal duration of ribavirin therapy.
Keywords: fecal shedding; hepatitis E virus; relapse; ribavirin therapy.
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