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. 2015 Jan 1;60(1):96-9.
doi: 10.1093/cid/ciu742. Epub 2014 Sep 23.

Protracted fecal shedding of HEV during ribavirin therapy predicts treatment relapse

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Protracted fecal shedding of HEV during ribavirin therapy predicts treatment relapse

Florence Abravanel et al. Clin Infect Dis. .

Abstract

Twenty-four solid-organ-transplant recipients with chronic hepatitis E virus (HEV) infections were given ribavirin therapy for 3 months. All the patients with protracted fecal HEV shedding during treatment suffered a relapse. Monitoring HEV fecal excretion could be used to determine the optimal duration of ribavirin therapy.

Keywords: fecal shedding; hepatitis E virus; relapse; ribavirin therapy.

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