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Case Reports
. 2014 Sep;24(5):318-20.
doi: 10.4103/0971-4065.133024.

Massive pleural effusion in a renal transplant recipient on tacrolimus

Affiliations
Case Reports

Massive pleural effusion in a renal transplant recipient on tacrolimus

L S Nayagam et al. Indian J Nephrol. 2014 Sep.

Abstract

Fluid and salt retention have been described as a side effect of tacrolimus therapy. We report a case of unexplained massive fluid retention with pleural effusion and ascites in the immediate post-transplant period. The patient recovered immediately on conversion from tacrolimus to sirolimus.

Keywords: Fluid retention; sirolimus; tacrolimus.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Chest X-ray on post-transplant day 5 showing a massive left pleural effusion
Figure 2
Figure 2
Chest X-ray 3 days after conversion to sirolimus

References

    1. Spencer CM, Goa KL, Gillis JC. Tacrolimus. An update of its pharmacology and clinical efficacy in the management of organ transplantation. Drugs. 1997;54:925–75. - PubMed
    1. BeDell LS, editor. 7th ed. St. Louis, MO: Mosby; 1997. Mosby's Complete Drug Reference Physicians GenRX; pp. 145–8.
    1. Randomised trial comparing tacrolimus (FK506) and cyclosporin in prevention of liver allograft. rejection European FK506 Multicentre Liver Study Group. Lancet. 1994;344:423–8. - PubMed
    1. A comparison of tacrolimus (FK 506) and cyclosporine for immunosuppression in liver transplantation The U.S. Multicenter FK Liver Study Group. 6 Li The US Multicenter FK506 Liver Study Group. N Engl J Med. 1994;331:1110–5. - PubMed

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