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Comment
. 2014 Sep 26;115(8):690-2.
doi: 10.1161/CIRCRESAHA.114.304632.

Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth

Cheng-Hai Zhang  1 , Bernhard Kühn  2
Affiliations
Comment

Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth

Cheng-Hai Zhang et al. Circ Res. .

Abstract

A recent study from Naqvi et al in Cell shows that in mice during preadolescence, cardiomyocytes undergo a burst of proliferation that is related to a thyroid hormone surge. This study challenges the conventional model of the timing of terminal differentiation and provides a direction for further mechanistic research on cardiomyocyte proliferation and differentiation.

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Conflict of interest statement

Disclosures

The authors have no financial conflicts of interest to declare.

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