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. 2012 Aug;72(8):740-743.
doi: 10.1055/s-0032-1315006.

Primary Malignant Vaginal Melanoma - Case Report and Review of the Literature

F Kühn  1 , M Dieterich  2 , E Klar  1 , B Gerber  2 , C Prinz  3
Affiliations

Primary Malignant Vaginal Melanoma - Case Report and Review of the Literature

F Kühn et al. Geburtshilfe Frauenheilkd. 2012 Aug.

Abstract
in English, German

With fewer than 250 cases published worldwide, primary vaginal melanoma is an extremely rare malignant entity which is mostly diagnosed in advanced stages. The estimated incidence of vaginal melanoma is 0.026/100 000 women per year. The poor prognosis for advanced tumour stages and different therapies used in very limited numbers of patients require precise preoperative staging and a planned interdisciplinary therapeutic approach.

Das primäre Melanom der Vagina ist mit weltweit weniger als 250 publizierten Fällen ein äußerst seltenes Malignom und wird meist erst im fortgeschrittenen Stadium diagnostiziert. Die Inzidenz des vaginalen Melanoms wird auf 0,026/100 000 Frauen pro Jahr geschätzt. Die schlechte Prognose bei oftmals später Diagnosestellung sowie die verschiedenen Therapieansätze bei sehr geringen Fallzahlen erfordern ein exaktes präoperatives Staging und eine interdisziplinäre Therapieplanung.

Keywords: malignant melanoma; multivisceral resection; vaginal tumour.

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Conflict of interest statement

Conflict of Interest None.

Figures

Fig. 1
Fig. 1
Vaginal tumour at the cranial end of the vagina (MRT).
Fig. 2
Fig. 2
Vaginal tumour with lymph node infiltration (MRT).
Fig. 3
Fig. 3
Immunohistology using melanoma monoclonal antibody, clone HMB45.
Fig. 4
Fig. 4
Detection of tumour cells using Masson-Fontana stain.
See this image and copyright information in PMC

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