Starting dialysis at eGFR >5 ml/min per1.73 m(2): are we barking up the wrong tree?
- PMID: 25265950
- DOI: 10.1038/ki.2014.164
Starting dialysis at eGFR >5 ml/min per1.73 m(2): are we barking up the wrong tree?
Abstract
Although the goal glomerular filtration rate (GFR) for chronic dialysis initiation is currently above 5 ml/min per 1.73 m(2), there is no convincing evidence that patients will benefit from this approach. With close follow-up of advanced chronic kidney disease patients, aiming to start dialysis at an estimated GFR (eGFR) less than 5 ml/min per 1.73 m(2) may result in the avoidance of potentially unnecessary end-of-life dialysis and could result in significant dialysis-free time for a large segment of the world's future dialysis population.
Comment on
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An instrumental variable approach finds no associated harm or benefit with early dialysis initiation in the United States.Kidney Int. 2014 Oct;86(4):798-809. doi: 10.1038/ki.2014.110. Epub 2014 Apr 30. Kidney Int. 2014. PMID: 24786707 Free PMC article.
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