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. 2014 Sep:1325:108-26.
doi: 10.1111/nyas.12529.

Strategy for prevention of cancers of the esophagus

Junichi Akiyama  1 , Leo Alexandre, Anushka Baruah, Navtej Buttar, Raghav Chandra, Allan B Clark, Andrew R Hart, Ernest Hawk, Daniela Kandioler, Sonja Kappel, Sheila K Krishnadath, Anamay Sharma, Ishtpreet Singh, Danielle Straub, George Triadafilopoulos, Asad Umar, Brigitte Wolf
Affiliations

Strategy for prevention of cancers of the esophagus

Junichi Akiyama et al. Ann N Y Acad Sci. 2014 Sep.

Abstract

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the animal reflux-inflammation models for Barrett's esophagus and esophageal adenocarcinoma; genomic/epigenomic analyses; eflornithine-based combinations; the molecular derangements that promote neoplastic transformation; the role of COX-2 inhibitors, proton pump inhibitors, and phase II trials in Barrett's adenocarcinoma; statins in chemoprevention and treatment of esophageal cancer; and biomarkers as potential targets in Barrett's adenocarcinoma.

Keywords: Barrett's adenocarcinoma; COXIBs, PPIs; OESO; animal reflux-inflammation models; biomarkers; elofrnithine; statins.

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