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Case Reports
. 2014 Dec;52(12):4425-7.
doi: 10.1128/JCM.02286-14. Epub 2014 Oct 1.

Chronic hepatitis E virus infection in a pediatric female liver transplant recipient

Ana Maria Passos-Castilho  1 , Gilda Porta  2 , Irene K Miura  2 , Renata P S Pugliese  2 , Vera L B Danesi  2 , Adriana Porta  2 , Teresa Guimarães  2 , João Seda  2 , Eduardo Antunes  2 , Celso F H Granato  3
Affiliations
Case Reports

Chronic hepatitis E virus infection in a pediatric female liver transplant recipient

Ana Maria Passos-Castilho et al. J Clin Microbiol. 2014 Dec.

Abstract

We describe a case of chronic hepatitis E virus (HEV) infection in a 13-year-old female liver transplant recipient with recurrent increased aminotransferase levels and acute cellular rejection. This finding demonstrates that chronic HEV infection can occur and should be further investigated in immunocompromised patients in Latin America.

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Figures

FIG 1
FIG 1
Phylogenetic tree reconstructed by the neighbor-joining method with common 304-nucleotide (nt) ORF2 sequences from 46 isolates, including 13 porcine isolates from Brazil, 2 human isolates from Brazil, and the 2 human isolates described in this study, Brazilh4 and Brazilh4.1 (highlighted in red). The GenBank accession number in parentheses, name of the country of origin, species from which it was isolated, and genotype/subtype of the isolate identify each viral strain. Bootstrap values of >50 are indicated for the major nodes as a percentage of the data obtained from 1,000 replicates (bar, 0.02 substitutions per site). Major branches indicate genotypes. Avian HEV is the outgroup.
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References

    1. Hoerning A, Hegen B, Wingen AM, Cetiner M, Lainka E, Kathemann S, Fiedler M, Timm J, Wenzel JJ, Hoyer PF, Gerner P. 2012. Prevalence of hepatitis E virus infection in pediatric solid organ transplant recipients – a single-center experience. Pediatr. Transplant. 16:742–747. 10.1111/j.1399-3046.2012.01740.x. - DOI - PubMed
    1. Halac U, Béland K, Lapierre P, Patey N, Ward P, Brassard J, Houde A, Alvarez F. 2012. Chronic hepatitis E infection in children with liver transplantation. Gut 61:597–603. 10.1136/gutjnl-2011-300708. - DOI - PubMed
    1. Aggarwal R. 2011. Clinical presentation of hepatitis E. Virus Res. 161:15–22. 10.1016/j.virusres.2011.03.017. - DOI - PubMed
    1. Halac U, Béland K, Lapierre P, Patey N, Ward P, Brassard J, Houde A, Alvarez F. 2012. Cirrhosis due to chronic hepatitis E in a child post-bone marrow transplant. J. Pediatr. 160:871–874. 10.1016/j.jpeds.2012.01.028. - DOI - PubMed
    1. Halleux D, Kanaan N, Kabamba B, Thomas I, Hassoun Z. 2012. Hepatitis E virus: an underdiagnosed cause of chronic hepatitis in renal transplant recipients. Transpl. Infect. Dis. 14:99–102. 10.1111/j.1399-3062.2011.00677.x. - DOI - PubMed

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