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Review
. 2014 Aug;76(4):308-15.
doi: 10.1007/s12262-013-0898-0. Epub 2013 Apr 21.

Surgical treatment of primary hyperparathyroidism: description of techniques and advances in the field

Muhammad Adil Abbas Khan  1 , Sadia Rafiq  1 , Sophocles Lanitis  1 , Farhan Arshad Mirza  1 , Lukasz Gwozdziewicz  1 , Ragheed Al-Mufti  1 , Dimitri J Hadjiminas  1
Affiliations
Review

Surgical treatment of primary hyperparathyroidism: description of techniques and advances in the field

Muhammad Adil Abbas Khan et al. Indian J Surg. 2014 Aug.

Abstract

Primary hyperparathyroidism is a disease commonly seen in patients above 60 years of age. It is the most common cause of asymptomatic or symptomatic hypercalcemia, usually found incidentally on routine check-ups. Surgical treatment is the only definitive treatment of choice in the symptomatic patient; however, it can also be employed in asymptomatic patients. First described in 1925, bilateral neck exploration is the gold standard of treatment for primary hyperparathyroidism. The recent interest in minimally invasive surgeries has led to better and improved techniques of neck exploration with improved cosmetic results and lesser chances of transient or permanent hypoparathyroidism due to inadvertent removal of normally functioning parathyroid tissue. These include unilateral neck explorations, minimally invasive parathyroidectomies and minimally invasive radio-guided parathyroidectomy. The intact parathyroid hormone assays have greatly added to the detection of normal and abnormal functioning glands, hence better surgical outcomes.

Keywords: Hyperparathyroidism; Minimally invasive surgical procedure; Neck dissection; Parathyroid hormone; Parathyroidectomy.

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References

    1. Ahuja AT, Wong KT, Ching AS, Fung MK, Lau JY, Yuen EH, et al. Imaging for primary hyperparathyroidism—what beginners should know. Clin Radiol. 2004;59(11):967–976. doi: 10.1016/j.crad.2004.04.005. - DOI - PubMed
    1. Eigelberger MS, Cheah WK, Ituarte PH, Streja L, Duh QY, Clark OH. The NIH criteria for parathyroidectomy in asymptomatic primary hyperparathyroidism: are they too limited? Ann Surg. 2004;239(4):528–535. doi: 10.1097/01.sla.0000120072.85692.a7. - DOI - PMC - PubMed
    1. Diaz-Aguirregoitia FJ, Emparan C, Gaztambide S, Aniel-Quiroga MA, Busturia MA, Vazquez JA, et al. Intraoperative monitoring of kinetic total serum calcium levels in primary hyperparathyroidism surgery. J Am Coll Surg. 2004;198(4):519–524. doi: 10.1016/j.jamcollsurg.2003.12.006. - DOI - PubMed
    1. Allendorf J, Kim L, Chabot J, DiGiorgi M, Spanknebel K, LoGerfo P. The impact of sestamibi scanning on the outcome of parathyroid surgery. J Clin Endocrinol Metab. 2003;88(7):3015–3018. doi: 10.1210/jc.2002-021095. - DOI - PubMed
    1. Brasier AR. Hyperparathyroidism and the metabolic responses to parathyroidectomy. In: Morris PJ, Malt RA, editors. Oxford textbook of surgery. 1. Oxford: Oxford Medical Publications; 1994. pp. 755–760.

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