Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Oct 3;9(10):e108998.
doi: 10.1371/journal.pone.0108998. eCollection 2014.

Prevalence of comorbidities and their impact on hospital management and short-term outcomes in Vietnamese patients hospitalized with a first acute myocardial infarction

Hoa L Nguyen  1 , Quang Ngoc Nguyen  2 , Duc Anh Ha  3 , Dat Tuan Phan  2 , Nguyen Hanh Nguyen  4 , Robert J Goldberg  5
Affiliations

Prevalence of comorbidities and their impact on hospital management and short-term outcomes in Vietnamese patients hospitalized with a first acute myocardial infarction

Hoa L Nguyen et al. PLoS One. .

Abstract

Background: Cardiovascular disease is one of the leading causes of morbidity and mortality in Vietnam. We conducted a pilot study of Hanoi residents hospitalized with a first acute myocardial infarction (AMI) at the Vietnam National Heart Institute in Hanoi for purposes of describing the prevalence of cardiovascular (CVD) and non-CVD comorbidities and their impact on hospital management, in-hospital clinical complications, and short-term mortality in these patients.

Methods: The study population consisted of 302 Hanoi residents hospitalized with a first AMI at the largest tertiary care medical center in Hanoi in 2010.

Results: The average age of study patients was 66 years and one third were women. The proportions of patients with none, any 1, and ≥ 2 CVD comorbidities were 34%, 42%, and 24%, respectively. Among the CVD comorbidities, hypertension was the most commonly reported (59%). There were decreasing trends in the proportion of patients who were treated with effective cardiac medications and coronary interventions as the number of CVD comorbidities increased. Patients with multiple CVD comorbidities tended to develop acute clinical complications and die at higher rates during hospitalization compared with patients with no CVD comorbidities (Odds Ratio: 1.40; 95% Confidence Interval: 0.40-4.84).

Conclusions: Our data suggest that patients with multiple cardiac comorbidities tended to experience high in-hospital death rates in the setting of AMI. Full-scale surveillance of Hanoi residents hospitalized with AMI at all Hanoi hospitals is needed to confirm these findings. Effective strategies to manage Vietnamese patients hospitalized with AMI who have multiple comorbidities are warranted to improve their short-term prognosis.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Prevalence of Selected Cardiovascular and Non-Cardiovascular Comorbidities among Patients Hospitalized with Acute Myocardial Infarction.
CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; GI, gastro-intestinal; CKD, chronic kidney disease.
See this image and copyright information in PMC

References

    1. Hosseinpoor AR, Bergen N, Mendis S, Harper S, Verdes E, et al. (2012) Socioeconomic inequality in the prevalence of noncommunicable diseases in low- and middle-income countries: results from the World Health Survey. BMC public health 12: 474. - PMC - PubMed
    1. Van Minh H, Ng N, Juvekar S, Razzaque A, Ashraf A, et al. (2008) Self-reported prevalence of chronic diseases and their relation to selected sociodemographic variables: a study in INDEPTH Asian sites, 2005. Preventing chronic disease 5: A86. - PMC - PubMed
    1. Boutayeb A, Boutayeb S, Boutayeb W (2013) Multi-morbidity of non communicable diseases and equity in WHO Eastern Mediterranean countries. International journal for equity in health 12: 60. - PMC - PubMed
    1. Gili M, Sala J, Lopez J, Carrion A, Bejar L, et al. (2011) [Impact of comorbidities on in-hospital mortality from acute myocardial infarction, 2003-2009]. Revista espanola de cardiologia 64: 1130–1137. - PubMed
    1. Schmidt M, Jacobsen JB, Lash TL, Botker HE, Sorensen HT (2012) 25 year trends in first time hospitalisation for acute myocardial infarction, subsequent short and long term mortality, and the prognostic impact of sex and comorbidity: a Danish nationwide cohort study. BMJ 344: e356. - PMC - PubMed

Publication types