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Review
. 2014 Dec;165(6):1261-5.
doi: 10.1016/j.jpeds.2014.08.042. Epub 2014 Oct 1.

Multicentric Castleman disease presenting with fever

Christiana Smith  1 , Cathy Lee-Miller  2 , Megan K Dishop  3 , Carrye Cost  2 , Michael Wang  2 , Edwin J Asturias  4
Affiliations
Review

Multicentric Castleman disease presenting with fever

Christiana Smith et al. J Pediatr. 2014 Dec.

Abstract

Multicentric Castleman disease (MCD) is a rare lymphoproliferative disorder that usually manifests with nonspecific symptoms, including fever and lymphadenopathy. Treatment of pediatric MCD varies greatly. A 21-month-old child was diagnosed with MCD after presenting with fever. He had incomplete response to initial therapy directed at interleukin-6, but improved with subsequent chemotherapy.

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