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Case Reports
. 2015 Jan;24(1):e15-6.
doi: 10.1016/j.jstrokecerebrovasdis.2014.07.026. Epub 2014 Oct 3.

Prothrombin complex concentrate (Beriplex P/N)-related renal and cerebral infarctions in a patient with warfarin-associated intracerebral hemorrhage

Shin-Yi Lin  1 , Sun-Chun Tang  2 , Li-Jiuan Shen  3 , Jiann-Shing Jeng  4
Affiliations
Case Reports

Prothrombin complex concentrate (Beriplex P/N)-related renal and cerebral infarctions in a patient with warfarin-associated intracerebral hemorrhage

Shin-Yi Lin et al. J Stroke Cerebrovasc Dis. 2015 Jan.

Abstract

A 45-year-old man receiving warfarin treatment suffered from an intracerebral hemorrhage. Four-factor prothrombin complex concentrate (PCC) was administered to correct coagulopathy. However, bilateral renal infarcts and a cerebral infarct developed on day 5 and 7, respectively after PCC administration. Although the occurrence of PCC-related thromboembolism is low, health care practitioners should closely follow-up the symptoms and signs of thrombosis after PCC administration.

Keywords: Prothrombin complex concentrate; renal infarct; stroke; thromboembolism; warfarin.

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