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Review
. 2014 Sep 22:8:1891-911.
doi: 10.2147/OPTH.S47778. eCollection 2014.

Pharmacotherapy for uveitis: current management and emerging therapy

Robert J Barry  1 , Quan Dong Nguyen  2 , Richard W Lee  3 , Philip I Murray  1 , Alastair K Denniston  4
Affiliations
Review

Pharmacotherapy for uveitis: current management and emerging therapy

Robert J Barry et al. Clin Ophthalmol. .

Abstract

Uveitis, a group of conditions characterized by intraocular inflammation, is a major cause of sight loss in the working population. Most uveitis seen in Western countries is noninfectious and appears to be autoimmune or autoinflammatory in nature, requiring treatment with immunosuppressive and/or anti-inflammatory drugs. In this educational review, we outline the ideal characteristics of drugs for uveitis and review the data to support the use of current and emerging therapies in this context. It is crucial that we continue to develop new therapies for use in uveitis that aim to suppress disease activity, prevent accumulation of damage, and preserve visual function for patients with the minimum possible side effects.

Keywords: clinical trials; immunomodulatory therapeutic agents; immunosuppression; inflammation; uvea.

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