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Review
. 2014 Sep 30;9(3):Doc23.
doi: 10.3205/dgkh000243. eCollection 2014.

Clinical characteristics of Staphylococcus epidermidis: a systematic review

Amirmorteza Ebrahimzadeh Namvar  1 , Sara Bastarahang  2 , Niloufar Abbasi  2 , Ghazaleh Sheikhi Ghehi  2 , Sara Farhadbakhtiarian  2 , Parastoo Arezi  2 , Mahsa Hosseini  2 , Sholeh Zaeemi Baravati  2 , Zahra Jokar  2 , Sara Ganji Chermahin  2
Affiliations
Review

Clinical characteristics of Staphylococcus epidermidis: a systematic review

Amirmorteza Ebrahimzadeh Namvar et al. GMS Hyg Infect Control. .

Abstract
in English, German

Staphylococci are known as clustering Gram-positive cocci, nonmotile, non-spore forming facultatively anaerobic that classified in two main groups, coagulase-positive and coagulase-negative. Staphylococcus epidermidis with the highest percentage has the prominent role among coagulase-negative Staphylococci that is the most important reason of clinical infections. Due to various virulence factors and unique features, this microorganism is respected as a common cause of nosocomial infections. Because of potential ability in biofilm formation and colonization in different surfaces, also using of medical implant devices in immunocompromised and hospitalized patients the related infections have been increased. In recent decades the clinical importance and the emergence of methicillin-resistant Staphylococcus epidermidis strains have created many challenges in the treatment process.

Staphylokokken sind ein Cluster Gram-positiver unbeweglicher nicht Sporen-bildender fakultativ anaerober Kokkenbakterien, die in die zwei Hauptgruppen Coagulase-positiv and Coagulase-negativ unterteilt werden. Staphylococcus epidermidis nimmt mit dem höchsten Anteil eine prominente Stellung unter den Coagulase-negativen Staphylokokken ein und ist die wichtigste Ursache klinisch manifester Infektionen. Auf Grund der verschiedenen Virulenzfaktoren und der besonderen Eigenschaften ist diese Species häufig Ursache nosokomialer Infektionen. Auf Grund der Fähigkeit zur Biofilmbildung und der Kolonisation auf verschiedenen Oberflächen sowie auf Grund des zunehmenden Einsatzes von Implantaten bei hospitalisierten und speziell bei immunkompromittierten Patienten ist ein Anstieg derartiger Infektionen zu verzeichnen. In den letzten Jahrzehnten stellen die klinische Bedeutung und die Entstehung von Methicillin-resistenten Staphylococcus epidermidis-Stämmen neue Herausforderungen an den Behandlungsprozess.

Keywords: Staphylococcus epidermidis; coagulase-negative staphylococci; nosocomial infections; virulence factors.

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Figures

Table 1
Table 1. Biochemical and laboratory characteristics of the Staphylococcus spp.
Figure 1
Figure 1. Circular representation of the sequenced S. epidermidis genome. Complete DNA sequence of S. epidermidis was obtained from GenBank accession numbers (AE015929).
See this image and copyright information in PMC

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