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. 2014 Jul;3(4):275-85.
doi: 10.2217/cns.14.28.

Validation of the Brain Symptom and Impact Questionnaire (BASIQ) to assess symptom and quality of life in brain metastases

Gillian Bedard  1 , Saurabh Ray, Liying Zhang, Liang Zeng, David Cella, Erin Wong, Cyril Danjoux, May Tsao, Elizabeth Barnes, Arjun Sahgal, Lori Holden, Natalie Lauzon, Edward Chow
Affiliations

Validation of the Brain Symptom and Impact Questionnaire (BASIQ) to assess symptom and quality of life in brain metastases

Gillian Bedard et al. CNS Oncol. 2014 Jul.

Abstract

Objective: To validate the Brain Symptom and Impact Questionnaire (BASIQ) version 1.0 for brain metastases.

Methods: Patients with brain metastases and their healthcare professionals (HCPs) assessed the relevance of the BASIQ on a 0-10 scale with 10 as extremely relevant.

Results: A total of 52 patients and 20 HCPs participated in this study. In total, 95% of HCPs and 85% of patients found all items relevant. Balance and walking ability were rated relevant by 100% of patients and HCPs. Headache, nausea, energy, memory and ability to do housework were also rated relevant by 100% of HCPs. Over 95% of patients determined the items of ability to do housework, tiredness, energy, vision, memory and putting ideas into words as relevant. There were no items rated below 7 by patients or below 5 by HCPs.

Conclusion: This study indicates that BASIQ version 1.0 has valid content items encompassing disease-related symptom and impact on daily living.

Keywords: BASIQ; brain metastases; content validation; quality of life; questionnaire.

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Conflict of interest statement

Financial & competing interests disclosure

This study was supported by an educational grant from AbbVie. Saurabh Ray is an employee of AbbVie.The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

Figures

<b>Figure 1.</b>
Figure 1.. Patient responses on whether each item was relevant (yes/no).
n = 52 patients.
<b>Figure 2.</b>
Figure 2.. Healthcare professionals' responses on whether each item was relevant (yes/no).
n = 20 healthcare professionals.
<b>Figure 3.</b>
Figure 3.. Healthcare professionals' responses on whether each item was inappropriate to patients (yes/no).
n = 20 healthcare professionals.
<b>Figure 4.</b>
Figure 4.. Healthcare professionals' responses on whether each item was upsetting to patients (yes/no).
n = 20 healthcare professionals.
See this image and copyright information in PMC

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