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. 1987;8(1):14-5.
doi: 10.1016/0167-5699(87)90825-5.

Suppression of IgE responses following inhalation of antigen A natural homeostatic mechanism which limits sensitization to aeroallergens

P G Holt  1 , J D Sedgwick  2
Affiliations

Suppression of IgE responses following inhalation of antigen A natural homeostatic mechanism which limits sensitization to aeroallergens

P G Holt et al. Immunol Today. 1987.

Abstract

Contract between immune cells and airborne antigens is limited in the upper respiratory tract (URT) by physical barriers such as mucous. But some antigen does penetrate the URT epithelium. In this article, Patrick Holt and Jon Sedgwick postulate the existence of back-up immune mechanisms which prevent sensitization to antigens which cross epithelial barriers.

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