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. 1984 Apr;5(4):99-105.
doi: 10.1016/0167-5699(84)90043-4.

Quantitative variation in la antigen expression plays a central role in immune regulation

C A Janeway Jr  1 , K Bottomly  1 , J Babich  2 , P Conrad  2 , S Conzen  2 , B Jones  1 , J Kaye  2 , M Katz  1 , L McVay  2 , D B Murphy  2 , J Tite  2
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Quantitative variation in la antigen expression plays a central role in immune regulation

C A Janeway Jr et al. Immunol Today. 1984 Apr.

Abstract

The analysis of la antigen function has focused primarily on allelic variants of Ia molecules. In this review Charles Janeway and his colleagues discuss evidence that quantitative rather than qualitative variation in Ia antigen expression had a major role in immunoregulation and immunologically mediated disease.

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