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Comment
. 2014 Oct;20(10):1097-9.
doi: 10.1038/nm.3714.

Protein breakdown precedes pancreatic tumor development

Sam R Holmstrom  1 , Kenneth P Olive  1
Affiliations
Comment

Protein breakdown precedes pancreatic tumor development

Sam R Holmstrom et al. Nat Med. 2014 Oct.
No abstract available

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Comment on

  • Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.
    Mayers JR, Wu C, Clish CB, Kraft P, Torrence ME, Fiske BP, Yuan C, Bao Y, Townsend MK, Tworoger SS, Davidson SM, Papagiannakopoulos T, Yang A, Dayton TL, Ogino S, Stampfer MJ, Giovannucci EL, Qian ZR, Rubinson DA, Ma J, Sesso HD, Gaziano JM, Cochrane BB, Liu S, Wactawski-Wende J, Manson JE, Pollak MN, Kimmelman AC, Souza A, Pierce K, Wang TJ, Gerszten RE, Fuchs CS, Vander Heiden MG, Wolpin BM. Mayers JR, et al. Nat Med. 2014 Oct;20(10):1193-1198. doi: 10.1038/nm.3686. Epub 2014 Sep 28. Nat Med. 2014. PMID: 25261994 Free PMC article.

References

    1. Nature. 2014 Sep 4;513(7516):100-4 - PubMed
    1. Nat Med. 2014 Oct;20(10):1193-1198 - PubMed
    1. Biochem Soc Trans. 1980 Apr;8(2):205-13 - PubMed
    1. J Exp Med. 2013 Jun 3;210(6):1137-51 - PubMed
    1. Cancer Cell. 2014 Jun 16;25(6):735-47 - PubMed

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