Neurocysticercosis

Abstract

Neurocysticercosis is the commonest parasitic disease of the nervous system in humans, and constitutes a major public health problem for most of the developing world. The clinical manifestations of Neurocysticercosis (NCC) largely depend on number of lesions, site, and host immune response against the parasite. Diagnosis is mainly based upon neuro imaging studies and is supported by antibody/antigen detection in the serum and occasionally the cerebrospinal fluid. Randomized controlled trials evaluating the clinical benefit of treatment with cysticidal agents have shown hastened resolution of lesions in most, and reduced seizure recurrence in some studies. Outcome is favourable in single lesion parenchymal NCC but is guarded in multiple lesion and extra parenchymal NCC.