PATTERN OF CONSANGUINITY AND INBREEDING COEFFICIENT IN SARGODHA DISTRICT, PUNJAB, PAKISTAN
- PMID: 25299747
- DOI: 10.1017/S0021932014000431
PATTERN OF CONSANGUINITY AND INBREEDING COEFFICIENT IN SARGODHA DISTRICT, PUNJAB, PAKISTAN
Abstract
Consanguinity is widespread in Pakistan. The majority of studies on consanguinity in Pakistan have been carried out in urban metropolitan areas, and data on rural populations are scarce. The present cross-sectional study was conducted in Sargodha district, upper Punjab, Pakistan where the majority of the population reside in rural areas. A random sample of 1800 married females belonging to six tehsils of Sargodha district was obtained and differentials in consanguinity rates and inbreeding coefficient (F) were investigated. The consanguinity rate was calculated to be 56.72% and the inbreeding coefficient was 0.0348. First cousin unions had the highest representation (49.11% of all marriages), and marriages up to distantly related/Biradari constituted 67.94% of all marriages. Among the six tehsils, consanguinity rates ranged from 50.38% in Bhalwal to 62.88% in Sillanwali. A high rate of consanguinity was observed in subjects speaking the Punjabi language, those with self-arranged/arranged-love marriages and those engaged in professional jobs. With respect to the occupation of husbands the highest consanguinity rate was found among landowners (77.59%; F=0.0539) and businessmen (62.62%; F=0.0377). However, consanguinity did not appear to be associated with rural/urban origin or literacy level. The data showed a wide variation in consanguinity rate and inbreeding coefficient across socio-demographic strata in the Sargodha district population. A comparison of Sargodha with other populations of Punjab also showed regional heterogeneity in the pattern of consanguinity, warranting further studies.
Similar articles
-
Consanguinity and its sociodemographic differentials in Bhimber District, Azad Jammu and Kashmir, Pakistan.J Health Popul Nutr. 2014 Jun;32(2):301-13. J Health Popul Nutr. 2014. PMID: 25076667 Free PMC article.
-
CONSANGUINITY AND INBREEDING COEFFICIENT IN TRIBAL PASHTUNS INHABITING THE TURBULENT AND WAR-AFFECTED TERRITORY OF BAJAUR AGENCY, NORTH-WEST PAKISTAN.J Biosoc Sci. 2016 Jan;48(1):113-28. doi: 10.1017/S0021932014000558. J Biosoc Sci. 2016. PMID: 26627887
-
Consanguinity and its socio-biological parameters in Rahim Yar Khan District, Southern Punjab, Pakistan.J Health Popul Nutr. 2016 May 20;35:14. doi: 10.1186/s41043-016-0049-x. J Health Popul Nutr. 2016. PMID: 27206989 Free PMC article.
-
Inbreeding coefficients and degree of consanguineous marriages in Spain: a review.Am J Hum Biol. 2003 Sep-Oct;15(5):709-16. doi: 10.1002/ajhb.10198. Am J Hum Biol. 2003. PMID: 12953183 Review.
-
Inbreeding and diseases: demographic, genetic, and epidemiologic perspectives.Epidemiol Rev. 1991;13:28-41. doi: 10.1093/oxfordjournals.epirev.a036072. Epidemiol Rev. 1991. PMID: 1765114 Review.
Cited by
-
Burden of congenital and hereditary anomalies in the war-affected territory at Pakistan-Afghanistan border.Asian Biomed (Res Rev News). 2023 Aug 1;16(6):299-309. doi: 10.2478/abm-2022-2033. eCollection 2022 Dec. Asian Biomed (Res Rev News). 2023. PMID: 37551354 Free PMC article.
-
Comprehensive genetic screening reveals wide spectrum of genetic variants in monogenic forms of diabetes among Pakistani population.World J Diabetes. 2021 Nov 15;12(11):1957-1966. doi: 10.4239/wjd.v12.i11.1957. World J Diabetes. 2021. PMID: 34888019 Free PMC article.
-
Consanguinity, inbreeding coefficient, fertility and birth-outcome in population of Okara district, Pakistan.Pak J Med Sci. 2021 May-Jun;37(3):770-775. doi: 10.12669/pjms.37.3.2263. Pak J Med Sci. 2021. PMID: 34104163 Free PMC article.
-
Consanguinity among individuals with diabetes in Pakistan: A cross-sectional study.PLOS Glob Public Health. 2025 Jul 24;5(7):e0004964. doi: 10.1371/journal.pgph.0004964. eCollection 2025. PLOS Glob Public Health. 2025. PMID: 40705774 Free PMC article.
-
Whole exome sequencing identifies a novel variant causing Neurodegeneration with Brain Iron Accumulation syndrome (NBIA) in a consanguineous Pashtun family.Neurogenetics. 2025 Aug 11;26(1):60. doi: 10.1007/s10048-025-00838-3. Neurogenetics. 2025. PMID: 40788509
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
