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Editorial
. 2014 Oct 15;5(19):8816-7.
doi: 10.18632/oncotarget.2544.

New targets for resistant prostate cancer

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Editorial

New targets for resistant prostate cancer

Timothy C Thompson et al. Oncotarget. .
No abstract available

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Figures

Figure 1
Figure 1. Overlapping androgen receptor (AR) and glucocorticoid receptor (GR) or overlapping AR and c-Myb target genes as therapy targets for castration-resistant prostate cancer
Recent studies point to a high priority gene set of potentially actionable therapy targets for castration-resistant prostate cancer. Anti-AR agents result in derepression of specific genes, including targets of GR and c-Myb, that function as transcriptional regulators of a subset of target genes that overlap with target genes of AR. Expression of these genes is related to adaptive drug resistance.

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