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Case Reports
. 2014 Aug;8(8):OD01-2.
doi: 10.7860/JCDR/2014/8428.4654. Epub 2014 Aug 20.

Clear Cell Carcinoma of Cervix in a 60- year-old Woman: A Case Report

Kumar Ramesh  1 , Shruthi S A  2 , Saraswati P  3 , Rathnamala M Desai  4 , Anil K  3
Affiliations
Case Reports

Clear Cell Carcinoma of Cervix in a 60- year-old Woman: A Case Report

Kumar Ramesh et al. J Clin Diagn Res. 2014 Aug.

Abstract

Clear cell carcinoma of cervix is a rare entity amongst cervical neoplasms especially post diethylstilbestrol era. It is hypothesised to have a bimodal distribution with spontaneous cases unrelated to DES exposure observed in elderly age group. We report a rare case of clear cell carcinoma of cervix (CCCC) in a 60-year-old Asian female with no history of diethylstilbestrol (DES) ingestion. She underwent radical hysterectomy and adjuvant radiotherapy and showed no signs of recurrence even after 6 moths of follow up. Review of relevant literature was done including possible aetiology, appropriate treatment and prognostic factors.

Keywords: Cervical cancer; Clear cell adenocarcinoma; Diethylstilbestrol; Human papilloma virus.

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Figures

[Table/Fig-1]:
[Table/Fig-1]:
Exophytic endocervical growth seen arising from the posterior lip of cervix
[Table/Fig-2]:
[Table/Fig-2]:
Microscopy shows cords of glandular epithelium infiltrating into myometrium (H&E 100x)
[Table/Fig-3]:
[Table/Fig-3]:
Higher magnification showing clear cells and glandular epithelium (H&E 400x)
See this image and copyright information in PMC

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