Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Sep:7S1:S469-72.
doi: 10.1016/S1995-7645(14)60276-5.

Evaluation of the antimalarial potential of Icacina senegalensis Juss (Icacinaceae)

Essien David-Oku  1 , Obiajunwa-Otteh Juliet Ifeoma  2 , Akuodor Godwin Christian  3 , Essien Augustine Dick  3
Affiliations
Free article

Evaluation of the antimalarial potential of Icacina senegalensis Juss (Icacinaceae)

Essien David-Oku et al. Asian Pac J Trop Med. 2014 Sep.
Free article

Abstract

Objective: To evaluate in vivo antimalarial activity of methanol leaf extract of Icacina senegalensis.

Methods: The extract was investigated for activity against early and established malaria infections using Swiss albino mice infected with Plasmodium berghei at dose levels of 25, 50 and 100 mg/kg. Chloroquine (10 mg/kg) was used as positive control.

Results: A dose dependent chemo-suppression of the parasites was observed at different dose levels of the extract tested with a considerable mean survival time.

Conclusions: The results support further investigation on components of traditional medicines as potential new antimalarial agents.

Keywords: Antimalarial agent; Herbal medicine; Icacina senegalensis; Leaf; Mice.

PubMed Disclaimer

LinkOut - more resources